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Abstract The salivary glands begin to form at 6-8 weeks’ gestation. The major salivary glands are the parotid, submandibular, and sublingual glands. Minor salivary glands are found throughout the submucosa of the upper aerodigestive tract with the highest density found within the palate. Tumors of salivary gland tissue constitute about 5% of head and neck tumors and affect major salivary glands five times more often than minor salivary glands. Most (80%) salivary gland neoplasms originate in the parotid gland, (10-15%) originate in the submandibular gland and the remainder occur in the sublingual and minor salivary glands. Tumors arising from minor salivary gland tissue carry an even higher risk for malignancy (75%). |