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العنوان
Impact of fetal lead exposure on cord blood Insulin like growth factor-I levels and neonatal anthropometric parameters\
الناشر
Ain Shams university.
المؤلف
Benyamen,Maged Moneir Maximous.
هيئة الاعداد
مشرف / Hassan Tawfik Khairy
مشرف / Abeer Salah El Din El Sakka
مشرف / Nehal Mohamed El Raggal
باحث / Maged Moneir Maximous Benyamen
الموضوع
fetal lead exposure. cord blood Insulin. neonatal anthropometric parameters.
تاريخ النشر
2011
عدد الصفحات
p.:155
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة عين شمس - كلية الطب - pediatrics
الفهرس
Only 14 pages are availabe for public view

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from 155

Abstract

This study was designed primarily to evaluate impact of fetal lead exposure as reflected by maternal and cord blood lead levels, on cord blood IGF-1 concentration and anthropometric measures at birth in term neonates.
The study included 50 randomly selected mothers, and their newborns, recruited from the Obstetrics Department, Obstetrics and Gynecology Hospital, Ain-Shams University. The study was conducted during the period from October 2010 to January 2011.
All mothers were subjected to complete history taking, physical examination, laboratory investigations which included, maternal blood lead level, cord blood lead level and cord serum IGF-1.
Statistical analysis was done to evaluate the different studied parameters.
The mean maternal blood lead level was (10.9ug/dl) with a range of (2-19ug/dl), and the mean cord blood lead level was (2.08ug/dl) with a range of (0-5ug/dl).
Our results revealed that, lead concentration in the umbilical cord was highly significantly correlated with the concentration of maternal venous blood lead (r= 0.665, P=0) but, there was no correlation between cord blood lead level and cord serum IGF-1 (r= -0.076, p=0.599).
There were no statistically significant differences between cord blood lead levels and neonatal anthropometric parameters.
Furthermore, in our study the cord serum IGF-1 was significantly correlated with birth weight of the newborns (r=0.322, p=0.023) but, had no correlation with other anthropometric parameters.