الفهرس 
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Abstract
Schistosomiasis is an ancient water-borne disease recorded by the Egypfians 4000 years ago. It is a world wide public health problern estimated to affect more than 200 million people in rural and urban areas of the world (Sniither’s and Doenhoff, 1982).
Colley j gj. (1972) and Warren (1972), stated that schistosomiasis is an immunological disease as the earliest manifestation is cercarial dematitis, due to hypersensitivity reaction of both immediate and delayed types.
Warren(1976) stated that the immunological changes in schistosomiasis were resulted mainly after egg deposition. This was due to granuloma formation around schistosome eggs trapped in the host tissues. Release of antigenic factors by secretory glands of mature miracidia was proven to be necessary for granuloma induction (Gigase, 1982 and Prata, 1982). PFèsei5.
T’ciFculátciii shLfbsoaal antigens, antibodies and iffimune complexes in sera of patients infected with schistosomlasis were previously demonstrated (Madwar and Voller, 1975 ; Philips and Draper, 1975 ; Bout j j. 1977 and Lawe1y.j ,j., 1979). Webbe (1981) and Wilson and Dixon (1981) stated that the soluble antigens in the circulation or extravascular fluids upon reaction with the corresponding antibodies lead to immune complex formation. These circulating immune complexes can attain wide spread vascular deposition or their localization may be confined primary to the glomerulus leading to glomeru1onephropahy.