الفهرس 
ACKNOWLEDGEMENTOnly 14 pages are availabe for public view
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Abstract
The adverse biochemical effects of acrylamide toxicity and the beneficial impacts of both turmeric (Curcuma Longa), and artichoke (Cy-nara Scolymus L) as anti-oxidant against acrylamide toxicity in rats were studied. One hundred and sixty adult male albino rats were used.40 rats were used for LD50 determination and the remaining 120rats were di-vided into eight equal groups, each of fifteen animals including; control group, acrylamide group, turmeric group, artichoke group, turmeric pro-tected group, artichoke protected group, turmeric treated group and arti-choke treated group. Acrylamide toxicity in an oral dose of 10.4 mg/Kg B.Wt increased lipid peroxidation in plasma, liver, brain and testes, in-creased nitric oxide concentration and ALT activity in serum , depletion of tissues GSH content, decreased GST and catalase activities, inhibition of CK , γGT and ChE activities and increased DNA fragmentation in liver, brain and testes.1% dietary turmeric supplementation and oral ad-ministration of 5% ALE either for protection or for treatment improved the adverse biochemical effects of acrylamide toxicity in serum and tis-sues. The treatment trails were more effective than protection trails.