الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Hypercholesterolemia (Literally: high blood cholesterol) is the presence of high levels of cholesterol in the blood. It is not a disease but a metabolic derangement that can be secondary to many diseases and can contribute to many forms of disease, most notably cardiovascular disease. It is closely related to the terms ”Hyperlipidemia” (elevated levels of lipids) and’ Hyperliporproteinemia” (elevated levels of lipoproteins Fifty (50) albino rats purchased from Research Institute of phthalmology, Giza, Egypt with average weight (125 ± 5g ) divided into ten grups(each of 5 rats ) , and housed in stainless steel cages under controlled condition. Body weight for each rat recorded at the beginning of the experiment and once a week for 4 weeks, and at the end of experimental period each rat weight recorded. The diet present to rats in special covered cups to avoid food loss. All rats provided with water by glass tubes through wire cage. The relative organs weight calculated. Rats divided into 10 groups, 5 rats in each group and feed the experimental diets for consecutive 28 days as follows: Group (1): Negative control (C-); rats fed on basal diet only. Group (2): Positive control (C+); rats fed on hypercholesterolemic diet composed of basal diet + 1,5 % cholesterol + 2 % saturated fat. SUMMARY 110 Groups (3): Rats fed on hypercholesterolemic diet + lemon flowers 5%. Groups (4): Rats fed on hypercholesterolemic diet+ lemon flowers 10%. Groups (5): Rats fed on hypercholesterolemic diet+orange flowers 5%. Groups (6): Rats fed on hypercholesterolemic diet+orange flowers 10%. Groups (7): Rats fed on hypercholesterolemic diet + lemon leaves 5 %. Groups (8): Rats fed on hypercholesterolemic diet+ lemon leaves 10 % Groups (9): Rats fed on hypercholesterolemic diet+ orange leaves 5 % Groups (10): Rats fed on hypercholesterolemic diet + orange leaves 10%. After four weeks rats were anaesthetized with diethyl ether. Blood was collected from hepatic portal vein in centrifuge tube, centrifuge for 10 min at 3000 r. p .m. the serum samples were placed in a dry and clean tube, and organs (liver, kidney, heart and spleen) were separated and washed with saline, then dried with filler paper and weighed, then stored at-18 ºC till analysis . 111 The results arrived at could be summarized on follows: Protein efficiency ratio (FER) data presented showed a leavel of 0.081 for normal control group , 0.11 for positive control group and the mean levels of group3: group10 wear 0.1 , 0.086 , 0.096 , 0.080 , 0.091 , 0.08 , 0.089 and 0.08 Concerning liver weight of the normal control group presented 5.125 ±0.34, 6.65 ±0.12for positive control group and the mean leavels of group3: group10 wear 5.425g 0.55 , 5.2g ±1.56 , 5.425g ±0.93 , 5.3g ±0.33 , 5.675g
±0.56 , 5.275g ±0.32 , 5.15g ±2.43 and 4.91g ±0.33.
Kidney weight of the normal control group presented
1.075g ±0.26, 1.3g ±0.76 for positive control group and
the mean leavels of group3: group10 wear 1.075g ±0.35 ,
1.015g ±0.09 , 1.025g ±0.18 ,0.975g ±0.17 , 1.25g ±0.28
, 1.05g ±0.37 , 1g ±0.46 and 0.9 6g ±0.44 .
Heart weight of the normal control group presented 0.5 g
±0.11, 0.675g ±0.29 for positive control group and the
mean leavels of group3: group10 wear 0.55 g ±0.19,
0.525g ±0.04, 0.6 g ±0.02 , 0.55 g ±0.03 , 0.60 g ±0.21 ,
0.535 g ±0.33 , 0.575 g±0.05 and 0.505 g ±0.66 .