الفهرس 
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Abstract
This study aims to assess the level of glycated hemoglobin (HbA1c)
in non diabetic iron deficiency anemic children and comparing it with the
control group.
Summary and Conclusion
Iron deficiency is the most common preventable nutritional
deficiency in the world and a major cause of anemia which is associated
with alterations in development and behavior, particularly during infancy
and toddlerhood when there is rapid growth and high need for iron.
Hemoglobin A1c is widely used as a measure of medium term
glycemic control over last 8-12 weeks in diabetics and as a surrogate marker
for risk of complications.
The relation between iron deficiency anemia and glycated
hemoglobin were studied in previous studies giving different results in
between.
Our study included Eighty five children age ranged between (1-10)
years, 51 children (the study group) selected from hematology clinic of El
Minia University Hospital over a period from may 2011 to December 2011,
they were diagnosed as iron deficiency anemia and before starting iron
therapy in addition to 34 children from apparently healthy children of
matched age were chosen as a control group they were subdivided into two
groups :
The first group included 51 (25 males and 26 females) non diabetic
children of newly diagnosed iron deficiency anemia depending on serum
iron and serum ferritin and sampling were done before starting iron therapy.
The second group included 34 (23 males and 11females) apparently
healthy children were taken as controls.
Complete blood count, serum iron, serum ferritin, serum fasting, 2h
post prandial glucose levels and Hb A1c were done for patients and controls.
Children with diabetes, hemoglobinopathies, blood transfusions,
negative smokers, salicylates abusers, cardiovascular diseases, bleeding tendency, organomegaly, lymphadenopathy, suspected malignancy, chronic
illness were excluded from the study.
The results showed that there was a highly significant decreases in
levels of Hb, serum iron, serum ferritin, among patients compared to
control group ( p value =0.001), also showed that the mean values of
HbA1c was highly significant higher in studied group than control
group (p value=0.001).
In conclusion the cause of elevated HbA1c in our study unclear but
we argued that elevated HbA1c levels in iron deficiency anemia could be
explained by the assumption that if serum glucose remains constant, a
decrease in the hemoglobin concentration might lead to an increase in the
glycated fraction.