الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
The present work was conducted on 9 Newzealand white bucks aged about 9-12 months with an average body weight of 3.5 kg at the begining of experiment. Throughout the whole period of experiments each animal received a concentrate commercial diet adlibitum and fresh water Our investigation was aimed to study: 1-Some alterations in semen characterestics of Newzealand white rabbits under the effect of f3-blocker (propranolol HCl) treatment. 2-Effect of addition of P-blocker (propranol HCl) in vitro upon the viability of rabbit spermatozoa. I- Some alterations in semen characterestics of Newzealand white rabbits treated with propranolol HCI. There are 314 ejaculate were collected from 9 Newzealand white bucks. 1- The reaction time of treated bucks were significantly prolongated following injection of 13-blocker propranolo HC1 than that recorded before treatment for both first and second ejaculates. The overall mean of reaction time was elongated following injection of propranolol HC1 (230.00+1.03) than before treatment (99.09+4.55). Moreover, there was a significant variation in reaction time among all individual bucks under investigation. However, buck number 7 can not ejaculate except after treatment. 2-The ejculate volume/ml of treated bucks were increased following injection of 13-blocker propranolo HC1 than that recorded before treatment for both first and second ejaculates. The overall mean of ejaculate volume was increased following injection of propranolol HC1 (0.75+0.03) than before treatment (0.63+0.03). Moreover, ther was a significant variation in ejaculate volume among all bucks in the present work. 3-The semen pH of treated bucks were decreased following injection of 13-blocker propranolo HC1 than that recorded before treatment for both first and second ejaculate. The overall mean of semen pH was decreased following injection of propranolol HC1 (7.34+0.02) than that before treatment (7.45+0.03). Moreover, there was variation among different bucks under investigation. 4-The mass activity of treated bucks were decreased than that before treatment for both first and second ejaculates. The overall mean of mass activity was decreased following injection of propranolol HCl (1.79+0.06) Than that before treatment (1.81+0.04). Moreover, there was a variation in mass activity of semen among different bucks under the present experimental condition. 5-The individual motility of treated bucks were decreased than that before treatment for both first and second ejaculates. The overall mean following injection of propranolol HC1 (46.99+1.21) than that before treatment (53.33+2.79). Moreover, there was a significant variation in the sperm individual motility among different bucks under study. 6-The cold shock resistance of treated bucks were decreased than that before treatment for both first and second ejaculates. The overall mean of cold shock resistance was decreased following injection of propranolol HC1 (18.71+0.86) than before treatment (23.28+1.24). Moreover, there was some variation in the cold resistance of spermatozoa among all under present investigation. 7-The live sperm percent of treated bucks were decreased than that before treatment for both first and second ejaculates. The overall mean of live sperm percent was decreased following injection of proparnolol HC1 (53.46+1.22) than that before treatment (60.43+1.69). Moreover, there was variation in live sperm among all examined bucks. 8-The sperm cell concentration of treated bucks were increased than that before treatment for both the first and second ejaculates. The overall mean of sperm cell concentration was increased following injection of propranolol HC1 (430.69+10.15) than before treatment (419.27+10.04). Moreover, there was variation among all bucks under the present work. 9-The primary sperm abnormalities of treated bucks were decreased than that before treatment for both first and second ejaculates. The overall mean of primary sperm abnormalities was decreased following injection of propranolol HC1 (4.26+0.18) than that before treatment (4.65+0.24). Moreover, there was variation among all bucks under investigation. 10-The proximal cytoplasmic droplet of treeated bucks were decreased than that before treatment for both first and second ejaculates. The overall mean of proximal cytoplasmic droplet was decreased following injection of propranolol HC1 (0.77+0.07) than that before treatment (1.00+0.10). Moreover, there was some variation in the proximal protoplasmic droplets among all bucks under present experimental condition. 11-The distal cytoplasmic droplet of treated bucks were decreased than that before treatment for both first and second ejaculates. The overall mean of distal cytoplasmic droplet was decreased following injection of propranolol HC1 (2.09+0.12) than that before treatment (3.93+0.24). In addition, there was some variation in distal protoplasmic droplets among all bucks under investigation. 12-The secondary abnonnalities of treated bucks were decreased than that before treatment for both first and second ejaculates. The overall mean of secondary abnormalities was decreased following injection of propranolol HC1 (2.43+0.16) than that before treatment (3.75+0.30). Moreover, there was slight variation in secondary sperm cell abnormalities among all examined bucks. 13-The total sperm cell abnormalities of treated bucks were decreased than that before treatment for both first and second injaculates. The overall mean of total sperm cell abnormalities was decreased following imjection of propranolol HC1 (9.57+0.43) than that before treatment (13.18+0.56). In addition, there was a significant variation in the total sperm cell abnormalities among all bucks under the present study. 2. Effect of addation of 13-blocker propranolol HC1 in vitro upon the viability of rabbit spermatozoa: The present study revealed that, the addition of P-blocker propranolol HC1 at concentration more than 31.35 mg% kill all rabbit speratozoa, while the addition of the drug at concentration 31.35 mg raises the sperm motility and livability during 60 minutes of incubation, then suddenly decreased after that up to 0% at 240 minutes. The addition of propranolol HC1 at concentration 15.62 increases the sperm motility and livability during 90 minutes of incubation, then it gradually decreased until reached to 0% at 510 minutes. Moreover, the addition of propranolol HCl at concentration 7.8 and 3.9 mg% raises the sperm motility and livability for a period of 150 minutes after that the motility and livability were gradually decreased after that till reached to 0% at 510 minutes preservation. The addition of I3-blocker propranolol HCl to rabbit semen at different concentration had no direct effect on the secondary sperm abnormalities during the first period of incubation. Moreover, the addition of propranolol at concentrations 31.35; significantly increased the secondary sperm cell abnormalities during 90 minutes of incubation and significantly increased till reaches its maximum level at 300 minutes of preservation. The addition of the drug at concentration 15.62 mg% significantly increase the secondary sperm abnormal during 90 minutes of incubation then it gradually decreased till reach its minimum level at 510 minutes. The addition of propranolol HC1 at 7.81 and 3.48 mg% caused significant increase the secondary sperm cell abnormalities at 300 and 360 minutes of preservation, then it gradally increased till reached its maximum value at 510 minutes of preservation.