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العنوان
A Study of Pharmacokinetic & Pharmacodyamic Interactions Between Sildenafil Citrate and Selected Antihypertensive Drugs /
المؤلف
Elmasry, Soha Mahmoud Ahmed.
هيئة الاعداد
باحث / سها محمود احمد المصرى
مشرف / سناء الجيزاوى
مشرف / محمد على عثمان
مشرف / سحر الغباشى الحجار
الموضوع
Pharmaceutical Technology.
تاريخ النشر
2013.
عدد الصفحات
p 269. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
تاريخ الإجازة
8/10/2013
مكان الإجازة
جامعة طنطا - كلية الصيدلة - Pharmaceutical Technology
الفهرس
Only 14 pages are availabe for public view

from 316

from 316

Abstract

Erectile dysfunction (ED) has a high prevalence among hypertensive men; the prevalence increases from 30% at the age of 50 years to 50% or more in patients aged over 70 years, i.e. 2-fold higher than that observed in normotensive subjects of the same age. The available studies have not clarified the factor playing a major role in the pathogenesis of sexual dysfunction in hypertensive men. Neurovascular factors, however, seem to be especially important, although hormonal and psychogenic factors cannot be excluded. The incidence of sexual dysfunction IS exacerbated by antihypertensive drug treatment. These drugs that are used to treat hypertension may cause EO. There is evidence that some classes of drugssuch as diuretics, centrally acting sympatholitic drugs, and o-blockers have a great impact on sexual function than other classes such as calcium antagonists and angiotensin converting enzyme inhibitors.