الفهرس 
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Abstract
Drug therapy of cardiac arrhythmia.s is based on a complex group of considerations. First, knowledge of the mechanism consequences and natural history of arrhythmia to be treated is enormously helpful. The response of an arrhythmia to drugs is as much a function of pathophysiological condition as it is to drug acti on Second, a clear understanding of the pharmacology of the drugs to be used is needed. This includes detailed knowledge of drug action on the electrophysiol— ogical properties of normal and abnormal cardiac tissues, of their effects on the mechanical properties
of the heart and vasculature and of their interactions with the autonomic nervous system and their effects on other organ systems.
Optimal therapy of disturbances of cardiac rhythm requires considerable knowledge of their pharmacokine— tics of antiarrhythmic drugs and how these parameters are affected by diseases. Finally a broad knowledge of adverse effects of the agents and their potential interactions with other drugs is necessary to monitor the course of therapy.