الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 112 |  |  |
| | | from | 112 | | |
Abstract
The present work was carried out on 24 clinically healthy
of both sexes and their body weight ranged from 10 to 20 Kg.
These animals were divided into 4 equal groups, each of 6 dogs.
The dogs of the first and second groups were subjected to
gastrojejunostomy and closure was with single-layer suture using
Coated Vicryl in first group and Dexon plus in the second group.
The animals of the third and fourth groups were subjected to
gastrojejunostomy and closure was with double-layer suture using
Dexo n plus in third group and- Coated Vicryl in fourth group.
Blood samples were taken one day before surgery and after
the 1~, the 2~, the 4th, and the 6th week following the operation
for determinat~on of serum level concentration of the total
proteins, cholesterol and calcium. In all groups serum level concentration
of totalprotetns revealed non-significant decrease
after the first week and significant decrease after the second
week. while it reached to the normal level at the 4th and the 6th
week -after operation. -Values of serum level concentration of
cholesterol revealed non-significant difference in serum cholesterol
Le ve.L before and after the 1~, the 2nd, the 4th week and
there was highly sign£ficant increase at the 6th week following
the operation. Serum level concentration of calcium revealed a
highly significant decrease up to 6th week.
-Clinically observation revealed that diarrhoea was not ob--
served in all groups. Vomiting occured in one case in group I and
one in group II. Anorexia was Deserved on nne ca~e in group II
and one in group IV. Positive radiographs were taken one month
postoperatively to estimate the patency of the surgical stoma and
the total emptying time.
Euthanasia for 3 animal, of Each group was performed at the 30 and 45 days postoperatively to evaluate the healing at the
site of anastomosis and to clearify whether there was adhesions
between the site of anastomosis and any interal organ in all
groups or not. There was marked adhesion between the site of
anastomosis and the omentum in one case in group II. The suture
material was absorbed and not ob.erved macroscopically in all
groups after one month. No ulceration was recorded on gastric or
jejunal side in all groups. The surgical stoma was flattened in
group I and group II, but in group III and group IV the surgical
stoma had irregular margin. The diamater of surgical stoma was
wider in group III and group IV (ranged from 2.0 to 2.3 em) than
in group I and group II (ranged from 1.4 to 1.8 em).
The best result of healing obtained with Dexon plus, this
was manifested microscopically by little lymphocytic infiltra~
tion. Good healing had also been obtained in those animals with
single-layer suture, this was manifested by little lymphocytic
infiltration, absence of suture material after one mont~ postoperatively,
little cc L’la ge nous fibres and the _site of anastomosis
appeared as normal tissues after 45 days. Double layer
produce greater damage to the underlying structure.
In conclusion the best healing obtained with single - layer
gastrojejunostomy with Dexon plus. The surgical atoma was smooth
and flattened. The suture material was not seen after one month,
little coll~genous fibera, little lymphocytic infiltration and
the site of anastomosiS was normally regained after 45 days.