الفهرس 
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Abstract
This work aimed at identifying mast cells in testicular biopsies from 30 patients
with nonobstructive azoospermia to assess the possible association between the
presence of mast cells and azoospermia. They were divided into 3 groups, group 1:
hypospermatogenesis cases, group 2: maturation arrest cases and group 3: Sertoli
cell only syndrome cases and mixed atrophy cases. The biopsies were stained with
haematoxylin and eosin stain for re-evaluation by Johnson score and with toluidine
blue stain for mast cells identifcation. Two types of mast cells, peritubular and
interstitial, were demonstrated in all sections with varied counts. Testicular sections
in group 3 showed a significant increase in both peritubular and interstitial mast
cells compared with other groups. Peritubular mast cell number was significantly
correlated negatively with Johnson score and interstitial mast cell number has no
significant correlation. The interstitial mast cells number demonstrates no
significant correlation with the ratio of tubules with sclerosis, while the number of
the peritubular mast cells shows a highly significant correlation. Interstitial and
peritubular mast cells number have a significant correlation with the ratio of Sertolionly
tubules. the number of the peritubular mast cells correlates significantly with
the degree of peritubular fibrosis, while interstitial mast cell number has no
significant correlation. There is no significant relation between the degree of
peritubular fibrosis and the histological diagnosis of all groups. It is concluded that
mast cell has a role in fibrosis which is a common finding in infertile patients,
proposing a new goal for medical treatment of infertile males.