الفهرس 
I-INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Obesity is defined as an accumulation of excess body fat, to such
an extent that health might be impaired. Dietarians use a body mass index
(BMI) to define obesity. Men and women with a BMI of 25.0 - 29.9
kg/m2 are considered over weight, and those with a BMI of 30 Kg/m2 or
greater are considered obese The present study has been carried out on
two hundreds of human being cases for the evaluation of body mass index
in Egypt, study of leptin and insulin correlations with BMI of all studied
groups. In the normal group studied cases, BMI was ranged from 18.5 -
25.9 which is slightly increased than reference BMI of WHO for normal
weight (18.5-24.9), in the over weight group studied cases, BMI was
ranged from 26 - 31.9 which is higher compared to WHO overweight
BMI (25.0-29.9) and the obese group also showed BMI higher than WHO
obese BMI as it measure more than 35.8.
The BMI study showed a highly significant difference between
over weight male patients (27.05 ±1.46) compared to male control t =
7.78, p < 0.001, obese male (44.06±2.91) compared to male control t =
12.30, p < 0.001, over weight female (28.59±0.84) compared to female
control t = 6.98, p < 0.002., obese female (46.15± 2.92) compared to
control female t =13.90 p < 0.001. Obese male (44.06±2.91) and over
weight male t = 13.5, p < 0.001, obese female (46.15 ± 2.92) and over
weight female t = 16.21, p < 0.001., over weight female (28±0.84) and
over weight male t = 3.31, p < 0.009. A significant difference was found
between female control (21.56 ± 2.38) and male control t=2.02, p<0.059.
Leptin level study showed a highly significant difference between
obese female patients (4.17±1.94) and obese male t=5.14 p<0.001, Also
there is a significant increase in control female (4.82±1.45) and control
Summary____________________________________________________
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male t=5.14 p<0.001, control female (4.82±1.45) than obese female
t=2.77 p<0.050, control male (1.84±0.34) and obese male t=.2.79
p<0.049
Insulin level study showed no significant difference between obese
male (9.28±1.61) and control male t = 0.040, p < 0.79, obese female
(9.06± 3.32) and control female t = 0.04 p < 0.096, female control
(9.16±5.18) and male control t = 0.05, p < 0.95, obese male (9.11±1.82)
and obese female t = 0.99, p < 0.34.
There is a highly significant difference between obese female
patients and obese male, a significant increase in control female and
control male control female than obese female control and obese male
control, a high significant difference in leptin level in obese male with
polymorphism and without polymorphism and obese male patients with
polymorphism than male control, a high significant difference between
obese male with polymorphism and obese female with polymorphism and
between obese male without polymorphism and female without
polymorphism, a significant difference between obese female with or
without polymorphism and obese female with polymorphism and female
control and also a significant difference between obese male without
polymorphism and control, While there is no significance between obese
female without polymorphism and obese female control .
The present study showed eight cases of obese patients three of
them showing polymorphism of obesity gene at 183 bp and 38 bp while
five cases without polymorphism at 221 bp using ladder 50 bp, nine
cases of obese patients showing polymorphism of obesity gene at 183 bp
and 38 bp using ladder 50 bp eleven negative cases 10 of them control
and one obese case patient without polymorphism normal at 221 bp using
ladder 50 bp.