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Abstract Probiotics are defined as non-pathogenic organisms that are incorporated into the diet to modify gut microbial ecology, leading to beneficial structural and functional changes in the gut. Interleukin-1 alpha is cytokine that participates in the regulation of immune responses, inflammatory reactions, and hematopoiesis. IL-6 acts as both a pro-inflammatory and antiinflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response. The aim of this study was to determine the effect of feeding a probiotics supplemented formula on serum level of IL1 and IL6 in infants in comparison to BF and those infants fed standard formula. This study was an open labelled prospective controlled study, performed on 72 full term apparently healthy infants aged between (1week-3months).They were recruited from healthy baby clinic and outpatient clinic of pediatric hospital of Ain Shams University during the period from May to November 2012. Studied infants were divided into 3 groups: Group I: 24 infants who were breast-fed included as a control group. Group II 24 infants were on standard formula. Group III 24 infants were on probiotic supplemented formula. |