الفهرس 
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Abstract
In Egypt, many antibiotics have been investigated for different
pharmacological effects. Stability studies are lacking. In the present
investigation, the stability of oxytetracycline, enrofloxacin, and
sulphadimidine was studied in vitro and in vivo. The effects of time,
temperature, pH, and different regions, s water on the process of the stability
were checked. The study included also the determination of chlorine
percentage and electrolytes percentage in drinking tap water and underground
water respectively. By the passage of time, the stability of the drugs used
decreased. As the temperature of the principal farm container increased, the
drugs stability decreased. Regarding the drugs pH, tetracyclines activity
increased in acidic pH, whereas fluoroquinolones, and sulphonamides
increased in alkaline pH. In vivo, sulphadimidine was more effective. It
saved 70 % of the tested chicken against E. coli artificial infection.