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Abstract The present study was designed to assess the impact of Myocardial Blush grade on Left Ventricular remodeling in patients undergoing successful emergency PCI in patients with ST elevation myocardial infarction. It included 30 consecutive legible patients with first acute STEMI. After written consent, all patients were submitted to full history taking, clinical examination, hemodynamic assessment, electro cardio- gram, laboratory findings, PCI intervention, and TIMI grading.Patients with TIMI grade-III were further submitted to MBG grading and echocardiographic assessment to detect cardiac remodeling. Echocardiogram was done at 24hours and 3 months post intervention. The results of the present study revealed that 8 patients (26.7%) had MBG 0; 7 patients (23.3%) had MBG I; 12 patients (40.0%) had MBG II and finally, 3 patients (10.0%) had MBG III. There was no significant difference between MB grades as regard age, sex or risk factors, but there was male sex predominance in studied cases. Chest pain was the main presenting symptom. Time from symptom onset and peak cardiac enzymes, were inversely correlated with MB grades. we find that there was significant reduction of LV function and increase of remodeling in patients with 0/I MBG grades and non significant changes with grades II/III after 3 months of PCI, as evidenced by echocardiographic parameters (EDV, ESV and EF%).Remodeling was presented in 11 patients (37%) and 63% of patients had no remodeling with increased remodeling in cases with grade 0/I. Conclusion Impaired MBG after emergency PCI is associated with increased risk of LV remodeling. It has the advantage of being simple method to assess myocardial microcirculation. |