الفهرس 
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Abstract
Candida isolation rate was 19.4% and 17.9% among patient group and personnel group respectively, with no environmental source.In patient group, C. albicans was the most commonly isolated specie (43.5%), NAC accounted for 56.5% with C. tropicalis as the commonest NAC spp.,followed by C. parapsilosis, C. glabrata,C.dubliniensis, C. krusei and lastly C. famata. While in personnel group, the commonest was C. parapsilosis.In the NICU, C. parapsilosis was the most commonly isolated specie.The difference between patients and personnel isolates in biofilm formation and hydrolytic enzymes production was not statistically significant.Biofilm formation, Proteinase activity and phospholipase activity were detected in 44.3%, 65.8% and 49.4% isolates respectively.Biofilm formation and Proteinase activity were significantly higher in NAC, while phospholipase activity was significantly higher in C. albicans. Almost all Candida species (99.8%) showed total hemolytic activity.Disk diffusion showed good agreement with broth microdilution method for antifungal susceptibility testing.Amphotericin B has excellent activity against all Candida species. Fluconazole activity was very weak against C. krusei and C. glabrata, while it was active against other Candida species.Voriconazole was more effective than fluconazole with low resistant rates among fluconazole resistant Candida (C. krusei and C. glabrata).PAPD typing is important for detecting relatedness between isolates in order to trace the source of infection and prevent the mode of transmission.