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العنوان
The relation between bacteriuria and HCV in patients with ileal neobladder /
المؤلف
Soliman, Wafaa Ezz El-Arab Ahmed.
هيئة الاعداد
باحث / وفاء عزالعرب أحمد سليمان
مشرف / رمضان حسن إبراهيم حسن
مشرف / حسن أبوالعنين عبدالباقى
مشرف / عصام محمود عبدالمنعم الصاوى
مشرف / محمد محمد عادل السكرى
الموضوع
Microbiology. Sulfamethoxazole. Antibiotics resistance.
تاريخ النشر
2013.
عدد الصفحات
206 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/2013
مكان الإجازة
جامعة المنصورة - كلية الصيدلة - Microbiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present study aims to determine the presence of bacteriuria and if it symptomatic or asymptomatic also to show extend of antibiotics resistance in patients with ileal neobladder. Overall 600 urine samples from the 200 patients underwent ileal w neobladder (between December 1991 and May 2010), collected from Urology and Nephrology Center, Mansoura University (UNC). The bacterial cultures for these patients were screened randomly at the first time and screened for 2nd and 3rd time after taking suitable antibiotics if they were positive growth.To show the role of horizontal gene transfer in Trimethoprim/Sulphamethoxazol resistant E. coli strain, first we examined the presence of type I and type II integron, in a total of 45 strains of E. coli, there were 20 (44.5%) strains contain type I integron, 9 (20%) strains contain type II integron and 10 (22.2%) strains contain both type and 6 (13.3%) strains were negative for both type of Integrons. Second by detection of sul gene in the same E. coli isolates. There were (43) strains capture Sul1 by 95%, (16) strains capture Sul2 by 35%, (14) strains contain both Sul1&Sul2 by 31% and only one strain carry Sul3 by 2.2%. According to association to type I integron, it was found that 27 (62. 8%) strains caring Sul1 was associated with type I integron and there was no connection between Sul2& Sul3 with type I integron. Then a sequencing to 7 samples contain type I& type II were done to show dfrs genes in both types, in this study there were dfr A1, dfr5 and dfr7.