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العنوان
Biochemical effects of ice tea on lipid metabolism in experimentally induced hyperlipidemia in rats /
المؤلف
Sorour, Reem Ibraheem Moqbel.
هيئة الاعداد
باحث / ريم إبراهيم مقبل سرور
مشرف / حسين عبد المقصود علي
مناقش / ياقوت عبدالفتاح السنوسي
مناقش / عفاف دسوقي عبد المجيد
الموضوع
Biochemistry Lipid Metabolism. Biochemistry.
تاريخ النشر
2010.
عدد الصفحات
139 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Analytical Chemistry
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة بنها - كلية الطب البيطري - الكيمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

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Abstract

The aim of this present study was to assess the hyperlipidemia
improving profile of ice black tea as a nutriceutical approach to hyperlipidemia in rats rendered hyperlipidemic by long term feeding on highfat and high cholesterol diet To assess this aim we used albino rats which were divided into seven groups,each consists of ten rats as follows: GROUP I : Rats were fed on normal diet and received no drugs; kept as negative control.GROUP II : Rats were fed on high-fat diet and received no drugs; kept as
positive control for all experimental groups.
GROUP III : Rats were fed on normal diet and received ice BT after 30 days
from the start of the experiment; kept as negative treated group.
GROUP IV : Rats were fed on high-fat diet and received ice BT after 30
days from the start of the experiment; kept as positive treated group.
GROUP V : Rats were fed on high-fat diet and received ice BT from the start
of the experiment; kept as prophylactic group.
GROUP VI : Rats were fed on high-fat diet and received atorvastatin after 30
days from the start of the experiment; kept as a standard treated group.
GROUP VII: Rats were fed on high-fat diet and received EZE after 30 days
from the start of the experiment; kept as standard treated group.
Serum samples were collected on the 30th, 45th and 60th days from the
start of the experiment and subjected for biochemical analysis. Tissue samples
were taken on the last day of the experiment for histopathological
examination. The following results were obtained:
SUMMARY
91
1- In normal rats, Ice BT extract caused insignificant changes in serum
total lipids concentration all over the period of the experiment; yet, its
administration significantly decreased serum total lipid concentration in
rats fed on high-fat diet
2- In normal rats, Ice BT extract caused insignificant changes in serum
cholesterol concentration all over the period of the experiment; yet, its
administration significantly decreased serum cholesterol concentration
in rats fed on high-fat diet
3- In normal rats, Ice BT extract caused insignificant changes in serum TG
concentration all over the period of the experiment; yet, its
administration significantly decreased serum TG concentration in rats
fed on high-fat diet
4- In normal rats, Ice BT extract caused insignificant changes in serum
HDL-C concentration all over the period of the experiment; yet, its
administration significantly increased serum HDL-C concentration in
rats fed on high-fat diet
5- In normal rats, Ice BT extract caused insignificant changes in serum
LDL-C concentration all over the period of the experiment; yet, its
administration significantly decreased serum LDL-C concentration in
rats fed on high-fat diet
6- In normal rats, Ice BT extract caused insignificant changes in serum
VLDL-C concentration all over the period of the experiment; yet, its
administration significantly decreased serum VLDL-C concentration in
rats fed on high-fat diet
7- In normal rats, Ice BT extract caused insignificant changes in serum
ALT concentration all over the period of the experiment; yet, its
SUMMARY
92
administration significantly decreased serum ALT concentration in rats
fed on high-fat diet
8- In normal rats, Ice BT extract caused insignificant changes in serum
AST concentration all over the period of the experiment; yet, its
administration significantly decreased serum AST concentration in rats
fed on high-fat diet
9- In normal rats, Ice BT extract caused insignificant changes in serum
urea concentration all over the period of the experiment; yet, its
administration significantly decreased serum urea concentration in rats
fed on high-fat diet
10- In normal rats, Ice BT extract caused insignificant changes in serum
creatinine concentration all over the period of the experiment; yet, its
administration significantly decreased serum creatinine concentration in
rats fed on high-fat diet
It could be concluded that ice BT has a good health impact in cases associated
with hyperlipidemia.