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Abstract Background/Purpose In bile duct carcinoma (BDC) Patients, bile aspiration cytology (BAC) is an established method for cytodiagnosis. The aim of this study was to evaluate the actual sensitivity of BAC and to evaluate the factors that Affect positive yields of BAC in patients with defined BDC. Methods Data on 50 consecutive patients with definite BDC, who underwent BAC, were collected. Fourteen factors were studied for association with positive BAC. Results the number of cytological samplings ranged from 1 to 14 times. The cumulative diagnostic yield was 70%, and 32 positive results were obtained at a maximum of six samplings. Independent factors associated with positive BAC were perihilar location, stricture lengthC2 cm, and macroscopic papillary type. Conclusion in BDC patients, repeated BAC is useful, and six times was the optimum number of repeat samplings. |