الفهرس 
Lichen Planus
P- selectinOnly 14 pages are availabe for public view
 |  | from | 126 |  |  |
| | | from | 126 | | |
Abstract
Lichen planus is an idiopathic, inflammatory, world wide, non infectious disease involving skin, mucous membranes and hair follicles. The cardinal features of LP are violaceous, polygonal, pruritic, flat-topeed papules with an overlying lace-like scales, which usually occur on the flexor surface of the extremities. P-selectin is an adhesion molecule located in the membranes of the α- granules of platelets and the Weibel–Palade bodies of endothelial cells and expressed on the surface of activated platelets and endothelial cells. It plays a significant and well documented role in occlusive vascular diseases by mediating leukocyte and platelet rolling and adhesion. The aim of this work was to study platelet activity, based on the plasma level of sP-selectin, in LP patients and to correlate between the degree of platelet activity and some clinical forms of the disease. This study included thirty patients with LP and 20 age and sex matched healthy persons as a control group.