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العنوان
Formulation Modeling and Simulation of the Excitation Propagation in Human Cardiac Tissues using Finite Element Method /
المؤلف
Shuaiby, Shuaiby Mohamed.
هيئة الاعداد
باحث / شعيبى محمد شعيبى
مشرف / عبد البديع عبد الحميد الشرقاوى
مناقش / جمال محمد محمد عبد الرحيم
مناقش / مدحت ابراهيم خشبة
الموضوع
Modeling.
تاريخ النشر
2013.
عدد الصفحات
103 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الهندسة الميكانيكية
الناشر
تاريخ الإجازة
28/7/2013
مكان الإجازة
جامعة أسيوط - كلية الهندسة - Mechanical Engineering
الفهرس
Only 14 pages are availabe for public view

from 117

from 117

Abstract

Biosimulation models of the heart action potential have become a very
useful tool. It provides better understanding for the complex biophysical
phenomena related to electrical activity in the heart such as cardiac
arrhythmias. At cellular level, the electrical activity of cardiac tissues
may be simulated by solving a system of ordinary deferential equations
(ODEs) describing the electrical behavior of the cell membrane. Because
the biophysical processes underlying this phenomenon are non-linear and
change very rapidly, the ODE system is a challenge to be solved
numerically. Furthermore, the implementation of these models is a hard
task for commercial finite element software. In this work a finite element
formulation, model and code generation of monodomain equation has
been conducted. The developed code is coupled with the modified
FitzHugh-Nagumo (FHN) cell electrophysiological model in order to
have isotropic excitation propagation starting from cell level to complete
heart level. MATLAB programming language was used to build the
proposed standalone finite element code. A two dimensional specimen of
heart tissues is simulated to show the behavior of the excitation
propagation and the repolarization phase for isotropic electrical activity.
Simulation results of the cardiac action potential have shown good
agreements with the experimental measurements.