الفهرس | Only 14 pages are availabe for public view |
Abstract IdentifYing areas of myocardium with depressed but potentially reversible contractile function may bear important significance in the therapeutic strategy and perhaps the prognosis of patients with coronary artery disease and left ventricular dysfunction (Rallimtoola, 1989). Consequently, the non-invasive assessment of dys-synergic but viable myocardium, which may contribute to the overall improvement m left ventricular function after revascularization; has generated great interest among cardiologists and cardiac surgeons (Brundage eta/., 1984). Among the several techniques used for this purpose, Tl- 20 I scintigraphy (using rest-redistribution or stressredistribution reinjection protocols) has been shown to be a useful method, largely based on the observation that the presence of thallium uptake’ in a myocardial region with depressed systolic function correlates with contractile improvement aticr rcvascularization (Ragosta eta/., 1993). Sestamibi unagmg IS commonly believed to underestimate viability; however its optimal nnaging characteristics are not completely explored. Gated-SPECT permits assessment of an original marker of viability; which is the radionuclidc myocardial wall thickening (RMWT), |