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Abstract ED is defined as the inability to achieve and/ or maintain an erection sufficient to permit satisfactory sexual intercourse.(3) Men with coronary heart disease (CHD) have a high prevalence of ED.(4) This association may be related to the fact that the same risk factors–i.e. hypertension, hyperlipidaemia, smoking and diabetes mellitus (DM) predict both ED and CHD(4-10). Endothelial dysfunction appears to be a common mechanism of disease progression for CHD and ED.(11) The aim of this work was to evaluate the prevalence and severity of organic erectile dysfunction and to evaluate the relation between ED and classical risk factors of CAD among men with documented coronary artery disease by coronary angiography and to study the relationship between severity of erectile dysfunction and the extent of coronary artery disease revealed by coronary angiography. This study was done on 300 patients above 18 years in Main University Hospital. The study was done during the period between October 2011 to March 2012. All patients were subjected to detailed history, clinical examination, routine investigations and coronary angiography. We used IIEF Questionnaire to define the presence and degree of erectile dysfunction. Erectile dysfunction was defined in 156 patients., 69 patients were mild ED,30 patients were mild to moderate ED,10 patients were moderate ED and 47 patients were severe ED. There were 42 (70%) patients have ED from 60 patients had DM,92 (59%)patients had ED from 157 patients had hypertention and 86 (60%) patients had ED from 145 smokers. This describe that the incidence of ED increases by the presence of risk factors as diabetes mellitus, hypertension and smoking(p<0.05). Our study revealed that there is statistically significant correlation between number of risk factors and the degree of ED by which the increased number of risk factors is associated with increase in the severity of ED. The link between ED and CAD has now been well established. Our findings showed that the prevalence of ED is relatively high in patients with CAD. Also, we found significant relation between ED degree and number of diseased vessels as the increased number of diseased vessels was associated by an increase in the severity of ED. We detailed the information about drug history of every patients individually with no significant relationship between type of drug and ED except for beta blockers (p=0.025). |