الفهرس | Only 14 pages are availabe for public view |
Abstract Amyl in (islet amylo1d polypeptide) IS 3 7 ammo acid peptide hormone mainly produced by islet beta cells, co-secreted with insulin. Actions of amylin is mainly exerted on fuel metabolism as it antagonises actions of insulin on skeletal muscles but not on adipose tissue so it stimulates process of glycogenolysis and increase lactalc turnover which acts as substrate for gluconeogensis in liver inc.reasiug hepatic glucose oulput. So amylin induces insulin resistance in skeletal muscles. Amylin inhibits insuliu seen:\ iou. Obesity is a very important risk factor 111 development of insulin resistance especially in patient with type II diabetes. |