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Abstract Post operative wound infection is stili one of the major complications that follow any surgical procedure. It is estimated that 325,000 post operative wound infections (POWI) occur each year in (USA) after emergency surgical procedures giving rise to annual cost between 130 and 845 million dollers/year (Khalil, l994). It can occur at any medical center all over the world, even at those applying the most recent and strict antiseptic measures (Lidwell et al., 1982). For any given type of operation, the development of wound infection will approximately double the cost of hospitalization (Alexander, l986). Reduction of sepsis will be beneficial for the patients themselves, for the hospital staff and for lhe community as a whoie. One of the methods to prevent (POWI) is the administration of prophylactic antibiotics in surgery, searching for the predisposing factors for (POWI) and the best method to reduce it, but no one has revealed 100% success (Alexander, 1985). In Ain Shams University hospitals, the POWI rate after general surgical procedures is common and ranging from as low as 15% to as high as over 67% giving rise to an annual cost between 4-12 million egyptian pounds/year. In addition to the health care costs, the morbidity and mortality that results from POWI are substantial and it is likely |