الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Hydrocarbons are widespread chemical substances in the environment characterized by association with a wide variety of cancers, which is a major cause of death and can be triggered by many factors that can be exogenous or endogenous. Studies show that some popular aliphatic, aromatic and polyaromatic hydrocarbons including halogenated subgroups hydrocarbons may increase the risk of cancer through a variety of mechanisms, including genotoxicity, tumor promotion, hormonal action and immunotoxicity, thus reviewed by International Agency for Research on Cancer (IARC) for having potential carcinogenicity. Associations with cancer have been reported in human studies for chemicals such as benzene, dioxins, formaldehyde and trichloroethylene. Benzene was correlated to acute myeloid leukaemia and other hematologic cancers in exposed workers dealing with petroleum products. Epidemiological studies indicate that exposure to dioxins leads to lymphoma and leukemia. Activation of AhR by TCDD resulted in loss of apoptosis response in three different lymphoma cell lines, which plays a key role in the development of cancer. Also many epidemiological studies discussed the relation of dioxin to lung cancer, prostate, multiple myeloma and soft tissue sarcoma. Nasopharyngeal- as well as lung cancers and leukameia- were associated with formaldehyde exposure. Trichloroethylene is closely related to lymphomas and renal cancer.