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Abstract INTRODUCTION The science or h<lCI!Hlrheolo!’\’, the llow proper!JCS ol’ the bi<Jod u11der phvsiologic & p<~tholo)!IC colldltl<li1S IJ<ts l>ecn introduced recc11tlv to explain SOlllC or the ver\ COnll1l<ll1 human diS<ISkr<lUS dtse<ISCS. Disturbed h<Jemorheology has hce11 umsidered to play a primary etiolo~ic role, not only in a classic dtscase like polvc~’lhaenn::t or sikle cell anae1nia hut <1IStJ in conditions like hvpertensio11 ”’”I di<~hetcs mellitus <lnd others. (Le rclle 1989) 1-hemorheologic<~l <JimorllJ<11ittcs ”’”” <!IStl pl<~v a role in arteri;ll thrombosis in general and IJ·equently accompanied in many cases by athero sclerosis and hyperlqmlaemi<J. These hemorheologic abnonnalites lll<l\’ he the determinant t:1ctors lll de<Jth or Jl<lticnts wllh these diseases ( Domu11u(r. 1983) In the microcuntlation where cells must del(mn to p<1ss throu[!h ll<llT<l\\ capillaries_ cellul<1r rhcolo~v II he ddimnabtlitv or 1ntlividual cells) IS the m::1_jor detenlllll<Hll ol”restsl:lllcc It) !low This <Jhil1tv to dd{nl!l lS ;Jiso <1 determill<lllt or the cell’s SUl\IVal tunc 111 c1rculat1on. The def(mn<~hilitv or the red cells lS essent1<1llv l1nked to 1ts structure (cellular ~enmetrv. membrane properties and cytoplasnllc viscosity) Thus structural ahnonn::dit1cs as I(HIIH.l Ill some haematulogJe<!l tllsmders can be expected to aiTeet blood llll\\ 111 the tllicroclrntlatHHl <IIlli ”’ted cell life (Stuart & Sash , 19911) Rllcologv is” rclativcrlv ne\\ disctplme ’” applied to the pr<!cticc or haematology. Rheological metllods IHJ\\ h<l\e sullicently good sensit1v1t\ & spcc1licity t(lr their appl1ctto11 to ” wtde v;metv of climc<~l tllsorders (Fedrova et a1, 1989) - I - |