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العنوان
BLOOD RHEOLOGY AND Its ALTERATION IN
VARIOUS PATHOPHYSIOLOGIC STATES
المؤلف
Taha;Khaled Moustafa
هيئة الاعداد
باحث / خالد مصطفى محمود
مشرف / بسيمة محمود العيسوى
مشرف / عزة صادق اليناصورى
مشرف / عفاف عبد العزيز عبد الغفار
الموضوع
Clinical Pmhology
تاريخ النشر
1998
عدد الصفحات
102 ص
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/1998
مكان الإجازة
جامعة عين شمس - كلية الطب - البابولوجيا الاكلينكية
الفهرس
Only 14 pages are availabe for public view

from 102

from 102

Abstract

INTRODUCTION
The science or h<lCI!Hlrheolo!’\’, the llow proper!JCS ol’ the bi<Jod
u11der phvsiologic & p<~tholo)!IC colldltl<li1S IJ<ts l>ecn introduced recc11tlv
to explain SOlllC or the ver\ COnll1l<ll1 human diS<ISkr<lUS dtse<ISCS.
Disturbed h<Jemorheology has hce11 umsidered to play a primary etiolo~ic
role, not only in a classic dtscase like polvc~’lhaenn::t or sikle cell anae1nia
hut <1IStJ in conditions like hvpertensio11 ”’”I di<~hetcs mellitus <lnd others.
(Le rclle 1989)
1-hemorheologic<~l <JimorllJ<11ittcs ”’”” <!IStl pl<~v a role in arteri;ll
thrombosis in general and IJ·equently accompanied in many cases by
athero sclerosis and hyperlqmlaemi<J. These hemorheologic abnonnalites
lll<l\’ he the determinant t:1ctors lll de<Jth or Jl<lticnts wllh these diseases
( Domu11u(r. 1983)
In the microcuntlation where cells must del(mn to p<1ss throu[!h
ll<llT<l\\ capillaries_ cellul<1r rhcolo~v II he ddimnabtlitv or 1ntlividual
cells) IS the m::1_jor detenlllll<Hll ol”restsl:lllcc It) !low This <Jhil1tv to dd{nl!l
lS ;Jiso <1 determill<lllt or the cell’s SUl\IVal tunc 111
c1rculat1on. The def(mn<~hilitv or the red cells lS essent1<1llv l1nked to 1ts
structure (cellular ~enmetrv. membrane properties and cytoplasnllc
viscosity) Thus structural ahnonn::dit1cs as I(HIIH.l Ill some haematulogJe<!l
tllsmders can be expected to aiTeet blood llll\\ 111 the tllicroclrntlatHHl <IIlli
”’ted cell life (Stuart & Sash , 19911)
Rllcologv is” rclativcrlv ne\\ disctplme ’” applied to the pr<!cticc or
haematology. Rheological metllods IHJ\\ h<l\e sullicently good sensit1v1t\
& spcc1licity t(lr their appl1ctto11 to ” wtde v;metv of climc<~l tllsorders
(Fedrova et a1, 1989)
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