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العنوان
Stem Cells :
المؤلف
Mashaly, Shady Ibrahim Mohammad Abdel-Slam.
هيئة الاعداد
باحث / شادى إبراهيم محمدعبدالسلام مشالي
مشرف / زينب أبوالفتوح جمعـة
مشرف / السيد صالح حسين
مشرف / أحمد أحمد حامد عيسى
الموضوع
Stem Cells. Psychiatry.
تاريخ النشر
2014.
عدد الصفحات
192 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب النفسي والصحة العقلية
تاريخ الإجازة
01/01/2014
مكان الإجازة
جامعة المنصورة - كلية الطب - Department of neuropsychiatry
الفهرس
Only 14 pages are availabe for public view

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Abstract

Stem cells (SCs) are commonly defined as cells capable of self-renewal through replication and differentiating into specific lineages. They have 3 main characteristics; self renewability, high plasticity and potency. Types of stem cells include embryo-¬derived stem cells, fetal stem cells, adult stem cells, and umbilical cord stem cells.The present essay aimed to review how stem cells can be useful in management of different psychiatric disorders.Research on the potential use of stem cell transplantation for AD has lagged Car behind that of many other neurodegenerative disorders. However, it was found that stem cells could provide a means to deliver neurotrophins to thediseased brain, potentially modulating endogenous synaptic plasticity and enhancing neuronal survival.The established iPSCs lines from schizophrenia patients with a defined DISC 1 mutation provided a useful resource for investigating the function of DISC 1 in human neurodevelopment either in Schizophrenia or ASD (with double diagnosis with either Schizophrenia or Bipolar disorders).MSCs may offer a novel therapeutic to ameliorate the immune abnormalities apparent in some children with autism.