الفهرس 
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Abstract
p-Diacetyl benzene 1 undergoes bromination to
afford p-bromoacetyl phenacyl bromide 2. Compound 2
reacts with twofold excess of malononitrile to afford 2-{2-
[4-(3,3 - Dicyanopropiony I )-pheny I] - 2-oxo-ethy l}-
malononitrile3. Compound 3 could be cyclized to afford
the l,4-phenylene-bis-furan derivative 4. Compound 3
reacts also with a twofold excess of hydrazine hydrate and
phenyl hydrazine under dry conditions to afford the bis
pyrazole derivatives 5a,b respectively. The reaction of
Sa,b with the same reagents in refluxing
dioxane/DMF( 4: 1) afforded the bis pyrazolopyridazine
derivatives 7 a and 7b respectively. The azo coupling of
compound 3 with arene diazonium salts afforded .the bis
pyrazoly derivatives 9a-c. The ~-keto esters 10a;b react
with benzaldehyde and malononitrile in a one pot
synthesis to afford the pyran derivatives lla,b. These
latter compounds react with hydrazine hydrate and urea
derivatives to afford the pyrano[2,3-c ]pyrazoles 15a,b and
the pyrano [2,3-d] pyrimidine derivatives 17a-d
respectively.