الفهرس 
The colonOnly 14 pages are availabe for public view
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Abstract
In this study, an animal model of rat experimental colitis was established using 2% acetic acid enema. The recovery process in the experimental rats was investigated using Propolis, Mesalamine and both Propolis & Mesalamine. It was a trial to mimic inflammatory bowel disease in human to understand its histopathological changes and to state possible methods for control.
Forty eight male albino rats were used and divided into six groups, each contained 8 rats. Control rats (group 1) were given 2ml saline enema. On the other hand, experimental rats were given 2% acetic acid enema once (group 2). In addition to acetic acid enema, the rest of experimental rats were treated with Propolis (group 3), 70% ethanol (sham control, group 4), Mesalamine (group 5) and both Propolis and Mesalamine (group 6) from the second day then sacrificed at day 8.
from each rat, the colon was dissected and the distal 8cm of the colon of each rat was excised, fixed in 10% formol saline and processed for paraffin sections. Serial sections of 5 um thickness were cut and stained with:
1. Hematoxylin and Eosin (H & E)
2. Periodic acid-schiff (PAS) for goblet cells.
3. Immunohistochemical technique for iNOS