الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Post-transplant diabetes mellitus is a common complication in renal allograft recipients. Recently, a high prevalence of DM has been reported among patients with chronic hepatitis C virus. The association between hepatitis C and DM appears to be fairly well demonstrated in the general population, although some controversy still exist. This work aimed to study the impact of HCV on the development of diabetes mellitus among Egyptian live-donor renal allo-transplant recipients.
Materials and Methods:
This retrospective single Centre study included 979 kidney transplant recipients who were transplanted at Mansoura urology & nephrology Centre between 2000& 2010 from which 66 patients were excluded, the remaining 913 patients divided into four groups according to HCV serology and diabetic status.
Results:
Pre-transplant dialysis duration and number of blood transfusion units were statistically significant among both viremic and non viremic groups. As regard induction therapy, a highly statistical significance was found between the four groups regarding presence& type of adjuvant therapy (p-value <0.001). As regard maintenance immunosuppression, High statistically significant results were found regarding steroid and rapamycin between four groups (p value <0.001) with lower significance regarding MMF (p-value 0.04) but no significance regarding azathioprine, cyclosporine or tacrolimus therapy. As regard NODAT, incidence was statistically higher in viremic versus non viremic group (P < 0.001).
Conclusions:
There is a positive correlation between incidence of NODAT and HCV.