الفهرس | Only 14 pages are availabe for public view |
Abstract Introduction The use of high ventilatory rates during CMV is limited byte minimum amount of time needed for a complete inspiration and expiration. New technologies to further increase the ventilatory rate and reduce the tidal volume led to the development of high frequency ventilation (HFV), which has been studied extensively in premature infants but with conflicting results. The most extensively discussed reasons for conflicting results included the ventilation strategies used for HFV and CMV, the age when HFV was started, and the ventilator technology and devices used. Aim of the study The current study aimed to evaluate the possible effects of rescue high frequency ventilation on different organs function namely, brain, liver and kidney of premature babies in comparison to the effects of conventional mode of ventilation Methodology Eighty-three preterm babies that were admitted to the Neonatal Intensive Care Unit (NICU) in Latifa Hospital (LH), Dubai Health Authority (DHA), Dubai, United Arab Emirates (U.A.E.), from December 2011 until January 2013 were enrolled in the study. All cases with initial provisional diagnosis of prematurity and/or respiratory distress that needed respiratory support at birth or soon after admission were admitted to NICU from labour suit or operation theatre. They were divided into 2 groups: Group A (Study group): Included forty-three preterm babies who were on conventional mode of ventilation (CMV) and needed High Frequency Ventilation (HFV) at a stage during the hospital stay due to failure of CMV. Group B (Control group): this included forty preterm babies who required conventional mode of ventilation ONLY. They were age, sex, weight matched newborn and had the same days on CMV. |