الفهرس 
Introduction and Aim of the WorkOnly 14 pages are availabe for public view
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Abstract
Our study was done on 100 patients who received allogenic HCT and divided into 50 patients myeloblative HCT and 50 patients non myeloblative HCT .
Retrospective collection of data including patients demography (age- gender- body weight – underlying disease ) , history of medical diseases (DM – HTN – RI ) ,pre- transplantation investigations (CBC – kidney function tests – liver function tests – eGFR – serum electrolytes – cyclosporine level ) ,post-transplantation investigations (serum creatinine – cyclosporine level ) , post-transplantation complications (SOS- ICU admission – TTP – CMV reactivation – acute GVHD ) and vital signs recorded daily during the exposure period . all these data were subjected to suitable univariable and multivariable analytical statistics to determine risk factors for AKI after BMT .
AKI was defined as doubling of baseline serum creatinine that might occurred in the 100 days after BMT which is considered stage 2 in RIFLE classification . In our study we found that :
1 - Neither age nor gender was associated with increased risk of AKI .
2 - Only history of HTN was associated with increased risk of AKI while history of DM or RI was not associated with increased risk of AKI .
3 - Occurrence of SOS (sinusoidal obstruction syndrome) after HCT was associated with increased risk of AKI , also patients who needed ICU admission after HCT was associated with increased risk of AKI , while CMV reactivation and development of acute GVHD was not associated with increased risk of AKI .
4 - Weight gain ( from base line pre transplant ) during exposure period was associated with increased risk of AKI and increased cyclosporine trouph level during exposure period was associated with increased risk of AKI , while development of fever or HTN during exposure period was not associated with increased risk of AKI .