الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Cancer represents the largest cause of mortality in the world. Cancer is characterized by uncontrolled cellular growth, local tissue invasion and distant metastasis. Cancer is largely a disease of older people; the median age for cancer diagnosis in industrial countries is approaching 70 years of age and is expected to increase. The disregulation of the immune function in the elderly population is referred to as ”immunosenescence”. Treatments include surgery, chemotherapy, hormonal therapy and radiation but they fail in preventing the metastatic spread of the disease through disseminated tumor cells so there was a need for immunotherapy that target tumor propagation without harming normal cells. An extremely promising strategy for cancer prevention today is immunotherapy especially adoptive cell therapy (ACT), which is defined as the isolation and reinfusion of T lymphocytes into patients to treat disease. White button mushroom maintain the health and can cure various diseases, including cancer without causing toxicity through its immune-modulatory properties by stimulating both non-specific and specific immunity.