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Abstract --~ =oe---,..- 0 y_-..____._.....,,~ • c 1: S· .. StosiSe vronLn nt fJ.ll t<-J:Til to scrvt.c as c=; control gro:1p• 15 pc_;ti;.;nts an~ 5 pati~nts ~ith ccl~mpsla. Lach case was invLstigatsd slong the follo~in~. lines: (l) I~cl~din6 naked ~nd ~icroscopic examination. ( 2) l<’rcsh ’ciop;::y f:com :.~11 c&scs stnin’-d 1 ~ ; 7 ” l; J 0 PLriodic Gcid-Schiff. v c.cn G i c s on • ~ 1 .r· ..£’ o.n v,rnoc.J.J.. h:.J u_l t;.::: pr,J-.Jclr:.r:-:p~;j_, -~ d ,clr:_;np;,,i,_._ :;how,:J t:ir_~t \\.’(_]]_ :cfin-~d ~J;- ttlo lo c 6. ’InicKt. ning, of t~~’~ bELSctncnt ;nunbranc. 7. J’ i bro sis und colL-~g>.--no .Ls transforms. tion o:; the villous stromo.. B. CongLstion of th~ villous capillarirs. c’j • lC. Prolifcrutivc c,rtcritis of t~~t: foetal vc.:::scls in vi ll o us s t c,_l.i:c s . Increased incidence o_.-_c intLrvillo~s fibrin deposition. ll. IncruclsLd inddcnc’ of fibrinoid dcgu:.rrltion of villi. on c:: ~” ~ s ’- v c r i t y o f t n ~...- d i s ’--’ c-t s L • tribution and (l) rl’hli’8 WUS 110 dL~fcrt-DCL in the dlstrib.J.tion of the four enzymes bE:-tv;cEn tht. normul, prc8clc:i .. L1ptic :’nd sclamptic groc1.p. (2) cholinG cstE-r,,_st.. wt.-l’’-- muinly locc:lizccl in tl1,, cJtoplasm of (J) LcucinL 2illlnopcptid~sc ~~s ~ound in pntchy areas tissJ.c stromG oi \lilli l oi olood vcss~ls. in norTi<_l one. ( ’ ’ L. / ,, ,) (1:5 c:scs). ,/.._, _- pr~-cc1nmptic Group (15 c~scs). ~:Jhov;c d no ell in the scvcrG ,’ SilD’::td Oc.CTv::::d ~ctivit._; in t!1c ;::i1d u-·uu.p cf prc.:- ~1. ...., ( ’; ) l s.tlO,<-d sli t incrL:c~:::<-- in tnc. s<_vcrc ljrt.-cclcJJJlptic grou.p. 1hc enzyme activity showed no chcngc in 80% showed T’hl Ecnzy;:lss which we cstir:utc.d nistoch’~ tlicc.lly are indicators of dcgLncrstivc ~roccss in pl~ccnt~l u.nits in prc-~clamptic toxaem1c.. pJ .c .nt:.l f:J.nction. ILL 0 J. Cll t foet~l welln~i in higi1 ri .sK. |