الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
The present study propose a novel preventive and therapeutic modality for two of the most common cancers, prostate (PCa) and melanoma using EGCG that addresses issues related to bioavailability. Concept of nanochemoprevention for cancer prevention could be developed as an inexpensive, tolerable and readily applicable approach for cancer control and management. Supportive data from these studies could pave the way for effective chemoprevention of cancer in human population. The present findings suggested that oral ready nanoformulation of EGCG (Chit-nano EGCG) was effective in both in vitro and animal model systems of Pca and malignant melanoma. This clearly indicates that using this system green tea polyphenols could be provided at physiologically achievable concentrations. The outcome from this study could thus have a direct practical implication and translational relevance to human PCa and melanoma patients. If everything falls into place at the right time with nanotechnology and its existing and forthcoming applications for cancer, success in the very near future could likely be expected.