الفهرس 
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Abstract
1- Worldwide, breast cancer is the most common form of cancer in females. It is the second most fatal cancer in women after lung cancer, and the number of cases has significantly increased since the 1970s, a phenomenon partly blamed on modern lifestyles in the Western world (Laurance, et al. 2006 ). 2-Surgical excision, chemotherapy and radiotherapy are the major therapeutic strategies used nowadays. These traditional therapies have, to some extent, dangerous side effects and so, biological therapy using tumor infiltrating lymphocytes (TILs) after their activation represents a promising approach to these problems. 3-The jujube (magic fruit) or Ziziphus jujube extract helps in many of vital activities and functions such as weight gain, antiallergenic, improving stamina and strength, mildly sedating, improving of liver function, stimulating the immune system, and helping to efficiently get the energy from food and giving energy. 4-The present study was done on a total of 18 female patients, all with breast cancer taken from the outpatient clinics of the NCI of Egypt. TILs were properly separated from the patients and treated by the magic fruit extract. 5-The results of the present study can be summarized as follows:-The mean value of the cell count after treatment by the magic fruit extract was significantly higher than before treatment (p< 0.001) indicating an excellent effect of the extract on increasing the number of cells after treatment. - Also, the mean value of IFN-? after treatment by the magic fruit extract was significantly higher than before treatment (p< 0.001). - The cell count was correlated to some of the liver and kidney function tests and not correlated to others. ALP was negatively correlated with the cell count before and after treatment. Urea was positively correlated with the cell count before treatment. Creatinin was positively correlated with the cell count after treatment. - IFN-? and both the liver and kidney function tests were nearly not correlated. The only significant correlation is that between creatinin and the IFN-? level before treatment. - No correlation could be detected between IFN-? level and the cell count before and after treatment with the magic fruit extract. -The clinicopathological data, including the tumor size, grades and stage as well as the lymph node status, were not associated with the cell count and IFN.