الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Worldwide, breast cancer is the most common cancer diagnosed among women and is the leading cause of cancer deaths.
The lymph node ratio (LNR), the ratio between the number of positive lymph nodes and the total dissected nodes, is a more comprehensive classification system to evaluate prognosis because it considers all the dissected nodes, whether positive or negative. All the individual studies until now have supported the LNR classification as a better prognostic predictor than pN staging. However, the current LNR studies still face certain limitations. First, aside from the lymph nodes, estrogen receptor (ER), progesterone receptor (PR), and human epithelial growth factor receptor 2 (HER2) status are just some of the other cancer indicators that should be taken into account when evaluating the value of lymph node classifications such as the number of positive nodes and the LNR. These other indicators are important prognostic and predictive factors in breast cancer and are fully considered in the intrinsic molecular subtype classifications including the luminal A, luminal B, HER-2/neu enriched, and basal-like (triple-negative) subtypes.
The present study was designed to examine the prognostic role of lymph node ratio on the survival of patients with breast cancer treated at a single institution and to high-light the clinico-pathological features and the outcome of predominantly among women who have that disease. It is a retrospective, open label analysis of patients with invasive non-metastatic breast cancer who underwent axillary lymph node dissection and had one or more positive axillary lymph nodes in Oncology Centre of Mansoura University in 6 years. All patients electronic records were reviewed for the following information: patient characteristics, diagnostic methods, histological features of the tumour including immunohistochemistry, number of dissected and positive lymph nodes, LNR, treatment details, recurrence data, survival, and cause of death.