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Abstract The thesis comprises three chapters. The first deals with the introduction where the literature survey on the natural multisite barbiturate compounds is introduced from different views. These compounds possess biological effects and are principally behave as hyponotic drugs and produce depressive effects on the central nervous system and the sensory and motor functions. Most of these compounds exert a pronounced physiological effect and are being studied in the fight against cancer. These are active as chemothera peutic and antineoplastic agents. The equilibrium and the coordination chemistry studies are given where a lack of data appeared. The plan of this research project is cons tructed based of Synthesis of some new azo and azo-methine compounds of barbituric and thiobarbituric acids and their cobalt mickel copper palladium and platinum complexes characterization of the organic compounds using and spectroscopy. Their electronic spectra are recorded in presence of different solvents and variable to assign the possible species present , mode of join inaction and electronic transitions. The values are evaluated spectrophotometrically and potentiometrically. The data are explained mainly from the electronic character requirements of the substituents. |