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Abstract N. sativa seeds and its oil have shown potential medical properties in traditional medicine because it has a very low degree of toxicity. N. sativa is a complex food additive with numerous components, some of which are contributory toward its antioxidant, anti-inflammatory, antimicrobial, cytoprotective and immunotherapeutic potential. This research aimed to study some biochemical, immunological and molecular effects of N. sativa in young and old aged rats. One hundred albino male rat of average body weight about 120- 250 gm were used in this study. Animals were kept in clean stainless cages under hygienic conditions ,fed on balanced ration and water was provided ad-libitum and left two weeks for acclimatization before the beginning the experiment. Animals were divided into four equal groups, each of group contain 25 rats as the following: Group 1: Control young rats (3 month old) were fed a standard diet and supplied with fresh clean water for 6 weeks. Group 2: Young rats (3 month old) were fed a standard diet and given orally a daily dose of N. sativa oil (1 ml/kg B. wt) for 6 weeks. Group 3: Control old rats (20 month old) were fed a standard diet and supplied with fresh clean water for 6 weeks. |