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Abstract Chronic abdominal pain is a common disorder in children and adolescents worldwide. It affects the child’s wellbeing, and the costs from missed school days and use of healthcare resources are high. Recurrent abdominal pain is one of the commonest complaints of childhood, affecting up to 10% of children at any one time. It frequently persists and is associated with adverse adult outcomes, including abdominal pain and psychological problems. The present study aimed toimprove the ability of family physician in the assessment and management of recurrent abdominal pain in children. A systematic review over the last 15 years, internet was searched for publications in the literatures, and journals, found that the two major categories in the differential diagnosis for chronic or recurrent abdominal pain in children and adolescents are organic disorders and functional disorders, Most children with chronic abdominal pain have functional disorders (conditions in which the patient has a variable combination of symptoms without any readily identifiable structural or biochemical abnormality). The study conclude that there are many factors relating to the incidence of RAP in children as; Imbalances of neurotransmitters, Food sensitivity mediated immunologically by immuno¬globulin G (IgG) |