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العنوان
Effect of Nutmeg on Parotid Salivary Gland in Adult Male Albino Rats :
المؤلف
Ramzy, Mary Moheb.
هيئة الاعداد
باحث / ماري محب رمزي
مشرف / ھاني عبد الحميد علي شريف
مشرف / محمد عبد السلام السخاوي
مشرف / محمد طھ حسين شريدح
الموضوع
Mouth. Teeth. Mouth - anatomy & histology. Mouth - physiology. Tooth - anatomy & histology. Tooth - physiology.
تاريخ النشر
2014.
عدد الصفحات
110 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Dentistry (miscellaneous)
تاريخ الإجازة
1/1/2014
مكان الإجازة
جامعة المنيا - كلية طب الأسنان - بيولوجيا الفم
الفهرس
Only 14 pages are availabe for public view

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Abstract

Haematoxylin and Eosin Stain Results:
The parotid gland of the control group (Group A) was composed of parenchyma which showed normal appearance of secretory acini and ducts; and fine C.T. stroma in between lobes and lobules and comprising rich capillary network.
As for the experimental group (Group B), the most noticeable changes were cytoplasmic vacuolations in acinar cells, dilatation of intercalated and striated ducts, congestion of blood vessels, signs of nuclear changes (pyknosis, karyolysis, karyorrhexis, hyperchromatism, etc.), lymphocytic infiltration, hyalinization of C.T. stroma and finally appearance of duct-like structures replacing severely atrophied acini. These changes gradually increased as the duration increased and as the dose administered increased.
Masson’s trichrome Stain Results: The experimental group showed more thickening of collagen fibers than in the control group.
PAS Reaction Results: Both the control and the experimental group showed acinar cells filled with PAS +ve substances. The basement membrane was also +ve to PAS. The epithelium lining of the ducts was –ve to PAS. However, numerous intracytoplasmic vacuoles were present in experimental subgroups 3 and 4 which gave –ve PAS reaction.
PCNA Immunohistochemical Results: The control group showed some weak +ve PCNA nuclei of the acini. In the experimental groups, the nuclei of the acinar cells revealed moderate +ve PCNA expression in subgroups 1 and 2, while in subgroups 3 and 4 both the nuclei of the acinar cells and the ducts revealed intense +ve PCNA expression. The cytoplasm of the acinar cells also showed weak +ve PCNA expression in subgroups 3 and 4.
Image Analysis Results: Significant increase in the blue binary colour was observed in the experimental groups with the increase of duration and with the increase of the dose of nutmeg extract as well.