الفهرس 
Introduction&Rationale.Only 14 pages are availabe for public view
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Abstract
Coronary artery disease is still one of the most prevalent health care problems in industrialized world. Cardiovascular imaging plays an important role in the diagnosis of coronary artery disease. In the last decades several non invasive functional imaging techniques such as single photon emission computed tomography (SPECT), magnetic resonance imaging and contrast echocardiography have become readily
available.(Underwood et al.,2004)
An intermediate coronary lesion on angiography is defined as a luminal narrowing with a diameter stenosis ≥40% but ≤70%. Assessment of a coronary lesion with intermediate severity continues to be a challenge for cardiologists. In the current era of drug-eluting stents (DES), when percutaneous coronary revascularization is achieved with high success, a low complication rate, and excellent long-term patency. it might be tempting to treat all suspect lesions with implantation of a DES. However, there are still procedural complications associated with angioplasty, the inherent risk of restenosis, and late stent thrombosis.(Stone et al.,2004)
In patients with chest pain and stenosis of moderate severity as assessed by coronary angiography, evaluation and treatment are challenging. Often, many diagnostic tests are performed and no clear diagnosis of the cause of the chest pain results. In a considerable number of patients, coronary revascularization is performed without definite evidence that the coronary stenosis is causing the symptoms.(Topol et al.,1993)
SPECT myocardial perfusion imaging (MPI) in particularly is generally wide used and is well established non invasive tool for the diagnosis of ischemic coronary disease. Reflecting the pathphysiological consequences of luminal obstructive CAD, this technique has proven to be highly accurate(Minz et al.,1996)
So the aim of this study to assess functional significance of border line coronary stenosis using stress-rest gated single photon emission computerized tomography myocardial perfusion imaging (SPECT-MPI).
This study carried out on 75 patients in Nuclear Cardiology Unit Ain Shams and suez canal University Hospitals who underwent coronary angiography and proved to have borderline lesion > 40 and < 70 % in one or more of the coronary arteries. (Stone et al.,2004).
We exclused Patients with acute MI,valvular heart disease and patients with decompensated heart failure
The result of this study showed that fifty eight males (77.3%) and seventeen females (22.7%).
Regards to different risk factors of coronary artery disease in the studied patient showed as the following the highest percentage of studied cases was hypertensive 82.7%, while smokers were 65%, diabetics 64%, dyslipidemia 56%, obesity 2.7% and stressful lifestyle 1.3%.