الفهرس 
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Abstract
This case-control study was conducted to assess the efficacy of phosphorylated insulin-like growth factor binding protein-1 (IGFBP-1) in cervicovaginal secretion between (24-34 weeks gestation) in diagnosis of preterm labor and the prediction of subsequent preterm delivery. It was performed at Outpatient Clinic and Emergency Obstetrics and Gynecology Department, Suez Canal University Hospital, Ismailia City. The patients were divided into two groups; control group included 30 asymptomatic patients and study group included 30 symptomatic patients who present with suspected preterm and complain of regular intermittent painful contractions occurring at least once in 10 minutes.
There was significantly higher mean of gestational age and Bishop Score in the pre-term group than full-term group (32.67 weeks and 8.53 versus 30.93 weeks and 3.07, respectively) (p≤0.01), while there was significantly lower mean of cervical length in the pre-term group than full-term group (2.21 versus 4.11, respectively) (p<0.0001). There were no statistically significant differences between both groups regarding mean weight, height and parity (p>0.05).
There was significantly higher frequency of pelvic pain in the pre-term group than full-term group (100% versus 53.3%, respectively) (p<0.0001).
There was significantly higher prevalence of positive actim Partus test in the pre-term group than full-term group (50% versus 16.7%, respectively) (p=0.006).
A strong phIGFBP-1-positive result predicted preterm delivery with a sensitivity of 50%, a specificity of 83.3%, a PPV of 75%, and a NPV of 62.5%.
There was significantly higher prevalence of previous preterm labor in the pre-term group than full-term group (60% versus 0%, respectively) (p<0.0001).
There was significantly higher frequency of symptoms of preterm labor in the pre-term group than full-term group (100% versus 13.3%, respectively) (p<0.0001).
There were significant positive correlations between the occurrence of pre-term labor and pelvic pain, Bishop Score, Actim Partus test, previous preterm labor and symptoms of preterm labor. There were significant negative correlation between the occurrence of pre-term labor and cervical length.