الفهرس 
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Abstract
The aim of this work was to study the clinical effect of
cryotherapy on the treatment of oral erosive lichen planus (OLP) in
comparison with topical corticosteroid.
In this clinical study, 20 patients that have been clinically and
histologically diagnosed with oral erosive lichen planus were
selected from Oral Medicine, Periodontology, Radiology and
diagnosis Department in Faculty of Dentistry, Alexandria University.
The patients were equally divided into two groups:
Study group (I): Ten patients were treated with cryotherapy
in two successive cycles of freezing and thawing 2 minutes each of
them.Control group (II): Ten patients were treated with topically
applied corticosteroid in form of orabase 4 times per day for 6
weeks.
Patients in the two groups were examined and re-evaluated for
pain scale (VAS) and lesion size score at four time follow up period;
base line, 10 days, one month, and three months.
Statistical analysis of the present study revealed a decrease in
the size score of the lesion and the pain measures in both studied
groups. However the decrease was not statistically significant.
Group (I): six patients presented complete remission of the
disease, and three patients showed improvement, while the last
patient showed relapse of lesion after two months of treatment with
cryosurgery treatment. In group (II): five patients presented
complete remission of the disease, and three patients showed clinical
improvement while two patients did not show any improvement.
The results of this study suggested that the cryotherapy
resembles the topical corticosteroid. Further studies are needed to
know the effect of cryosurgery in the treatment of EOLP.