الفهرس 
Introduction
Wheat germ oilOnly 14 pages are availabe for public view
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Abstract
This study aimed to evaluate some physiological effects of wheat germ oil on rats. So applaying two experiments, the experiment I was carried out on control and hypercholesterolemic rats and the experiment II was carried out on control and streptozotocin-diabetic rats.The experiment I: Carried out on control and hypercholesterolemic rats and evaluated the effects of wheat germ oil (WGO) administered orally to rats at two dose (300& 500mg/kg B.wt) on serum lipid profile & risk of atherosclerosis, serum testosterone hormone, leydig cells number, oxidative stress marker (Malondialedehyde (MDA)) and antioxidant enzymes (Superoxide dismutase (SOD), Catalase (CAT) & Reduced glutathione (GSH)) levels in liver, testes and brain tissue homogenates after the end of the experimental period that extended for six weeks. This experiment was carried out on thirty mature male Sprague dawely rats, divided into six groups (five rats in each) as follows: Groups (1): Control negative rats fed basal control diet. Group (2): Rats fed basal control diet and treated with WGO 300 mg/kg B.wt daily. Group (3): Rats fed basal control diet and treated with WGO 500 mg/kg B.wt daily. Group (4): Control positive rats fed a cholesterol-rich diet. Group (5): Rats fed a cholesterol-rich diet and treated with WGO 300mg/kg B.wt daily. Group (6): Rats fed a cholesterol-rich diet and treated with WGO 500 mg/kg B.wt daily. After the end of the experimental period (6 weeks), all rats were fasted overnight, deeply anaesthetized, blood samples collected from retro orbital plexus and serum separated for determination of lipid profile and testosterone hormone level. Tissue specimens were taken from liver, heart with aorta, testes and brain of all rats. Tissue homogenates of liver, testes and brain were used for determination of (MDA, SOD, CAT and GSH). The reminder of liver, testes and brain tissue specimens in addition to heart with aorta were fixed in 10% formalin for histopathological examination. Additionally the stained H&E testes slides were used for counting leydig cells number per testis of all rat groups.