الفهرس 
Neonatal Assisted VentilationOnly 14 pages are availabe for public view
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Abstract
prospective observational follow up study was
conducted in NICU of Ghamra Military Hospital to
compare CPAP and invasive IPPV ventilation as regards risk
factor and complication. One hundred and twenty neonates
were included over a period of one year with the diagnosis
of respiratory distress necessitating ventilator support.
Studied neonates are compared according to gestational age,
birth weight, gender, mode of delivery. Lastly maternal
diseases and medications. They also compared according
initial mode and duration of ventilation.
Results
According to our study PROM was the most frequent
maternal disorder within the studied neonates, followed by
pregnancy-induced hypertension and antepartum
hemorrhage. .The most frequent initial diagnosis in the
studied neonates was RDS, followed by TTN, then
pneumonia. Initial IPPV group were significantly more
immature and smaller in size than initial CPAP group. They
also had significantly lower 1- and 5- minute APGAR scores
and higher Fio2 needs than initial CPAP group.
There was statistically significant lower platelet count
and higher CRP in IPPV group compared to CPAP group.Neonates with initial IPPV had significantly more
chest x-ray findings, sepsis, nasal necrosis, NEC, laryngeal
edema, and higher rate of death. They were significantly
more acidotic with higher co2 levels. Within CPAP babies,
none of the complications was affected by the gestational age
being above or below 30 wks. Duration of CPAP above one
week was significantly associated with higher failure rate,
higher percentage of cranial US abnormalities and higher rate
of death.
Statistically significant higher percentage of infants
who failed CPAP had chest x-ray findings infants and cranial
US abnormalities and a significant portion of them died in
comparison to those who succeeded on CPAP.Higher
secretion, NEC and died infants in group C compared to
group B.
There was statistically significant association
between higher ventilator settings and GA (<30 wks), Males,
CS and PH (<7.2).
Babies who were in need for re-intubation had lower
gestational age and body weight, but these differences were
not statistically significant. Statistically highly significant
positive correlation between invasive ventilation duration
and sepsis, NEC and laryngeal edema.