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Abstract This study was conducted at El-Mahalla Chest Hospital on 115 subjects (100 workers exposed to cotton dust from Misr Company for Spinning and Weaving and 15 healthy subject not exposed to cotton dust) in the period from July 2013 to February 2014. The study protocol was approved by ethical committee Faculty of Medicine, Ain Shams University. These subjects were classified in to 5 groups:- Group I: 15 healthy subjects not exposed to cotton dust (control group). Group II: 25 workers works at weaving. Group III: 25 workers works at spinning. Group IV: 25 workers works at opening of cotton bales. Group V: 25 workers works at carding. Exclusion criteria:- 1- Previous exposure to other occupational dust such as Silica, Coal dust. 2- Those with history of smoking. 3- Those with previous history of asthma or COPD before Joining to the work.Patients were subjected to the following:- 1. Full history taken. 2. A standardized questionnaire was patterned according to American Thoracic Society (ATS) questionnaire (Ferris, 1978). Questionnaire collected information on complete work history, respiratory symptoms such as (cough, expectoration (sputum), wheezing, dyspnea, grade of chest tightness), and smoking history. 3. Physical measurements: Including weight, and height of each subject and BMI. 4. Clinical examination of chest. 5. Plain chest X ray (postero-anterior) view. 6. Spirometric pulmonary functions test was performed using ”CHEST GRAPH H I - 105- Japan” apparatus which measure: (FEVI%, FVC%, FVC/FEV1%, PEFR% and MMEF %). The present work revealed that:- • There was a highly significant statistical difference on comparing presence of respiratory symptoms between control group and cotton exposed groups. • There was significant statistical difference on comparing the presence of respiratory symptoms between control group and weaving, spinning, opening of cotton bales and carding groups.• Respiratory symptom was the highest prevalent in spinning and weaving workers. • Cough, expectoration and chest tightness were the highest prevalent symptoms in cotton exposed groups. • Cough, expectoration were the highest prevalent in spinning and weaving workers. • There was significant statistical difference on comparing FEVI% between control group and cotton exposed groups. • There was significant statistical difference on comparing FVC% between control group and cotton exposed groups. • There was significant statistical difference on comparing FVC/FEV1% between control group and cotton exposed groups. • There was significant statistical difference on comparing PEFR % between control group and cotton exposed groups. • There was no significant statistical difference on comparing MMEF% between control group and cotton exposed groups. • There was positive correlation between presence of respiratory symptoms and duration of exposure to cotton dust, the longer the duration of exposure to cotton dust the higher the presence of respiratory symptoms. • There was no correlation between period of exposure to cotton dust and spirometric functions. |