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العنوان
Role Of Oral Linoleinic Acid (Omega 3 Fatty Acids) In Meibomian Gland Dysfunction /
المؤلف
Owis, Walaa Abd El Moeti Tawfik.
هيئة الاعداد
باحث / عزة محمد شعبان حسانين
مشرف / شريف احمد كمال
مشرف / محمد ياسر سيد سيف
مشرف / وليد محمد مهران
الموضوع
Meibomian glands. Tears physiology.
تاريخ النشر
2014.
عدد الصفحات
112 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب العيون
تاريخ الإجازة
1/12/2014
مكان الإجازة
جامعة بني سويف - كلية الطب - طب وجراحة العيون
الفهرس
Only 14 pages are availabe for public view

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Abstract

Meibomian gland dysfunction (MGD), also known as posterior blepharitis is named after the glands located at the rim of the eyelids. The glands produce an oily substance that prevents the evaporation of the tear film. This is called the lipid layer which is the outermost layer of the tear film.
Each eye has approximately 50 glands on the upper eyelids and 25 glands on the lower eyelids. When these glands get infected they get clogged by a thick waxy secretion which hinders the natural flow of the oil causing meibomian gland dysfunction.Thus MGD could be considered one of the most common causes of dry eye.
Common symptoms of MGD can be similar to those of dry eye and blepharitis in general, such as itching, burning and excessive tearing. Other symptoms are foreign body sensation and a feeling of sand or grittiness in the eye. Specific symptoms of MGD are redness of the eyelids and small pimple like swellings of the upper and lower eyelids.
Treatment of MGD requires multiple level of treatments. So proper diagnosis and starting out with the correct treatments as soon as possible will be important for getting to a high comfort level.
Lines of treatment include; regular warm eyelid compresses and massage, artificial tears particularly those that replace thelipid layer, antibiotics (topical and systemic), finally vitamins and supplements as omega 3 fish oil and flaxseed oil.
99 In our study we aimed to study the role of omega 3 fatty acids ( oral Linoleinic acid) in treatment of MGD.
Fifty patients underwent full medical history and complete ocular examination during the first visit including; visual acuity, intraocular pressure, slit lamp and fundus examination.
After receiving oral omega-3 dietary supplementation consisting of one 1000-mg capsules once daily all patients we assessed after 6 weeks and 3 months.Patients were asked about symptoms of ocular irritation, itching, lid hyperemia, photophopia, foreign body sensation and dry eye sensation.
Objective clinical measures include;tear production (Schirmer I); tear film stability (fluorescein TBUT), ocular surface health (fluorescein surface staining), Tear meniscus height, plugged meibomian gland orifices and eye lid telangiectasia
After 3 months of follow up we noticed much improvement in patient symptoms and signs.
Omega 3 diatery supplementation proved to be effective in treatment of MGD.