الفهرس 
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Abstract
The burden of chronic disease on health care services worldwide is growing and the increased development of educational interventions which help patients to better manage their conditions is evident internationally. It has been recognized that poor adherence can be a serious risk to the health and wellbeing of patients. Adherence to fluid restrictions, dietary and medication guidelines as well as attendance at prescribed at hemodialysis sessions of a hemodialysis regimen are essential for adequate management of chronic kidney disease. The objective of the present study is to investigate the effect of an educational program on adherence to therapeutic regimen among chronic kidney disease stage 5 (CKD5) patients under maintenance hemodialysis at king Fahd Unit and Hemodialysis Unit, Cairo University Hospital Arab Republic of Egypt. To fulfill the aim of this study, the following research hypothesis was formulated: There would be no significant difference of patient’s adherence scores before and after implementation of the program. A purposive sample of sixty adult male and female patients on maintenance hemodialysis for at least 6 months and not more than one year were assigned, the sample was selected from King Fahd Unit and Hemodialysis Unit, Cairo University Hospital Arab Republic of Egypt. Socio-demographic and medical data sheet, Laboratory investigation assessment data sheet, Pre/post knowledge assessment data sheet and adherence assessment data sheet were utilized for data collection. The study results revealed, the post total mean knowledge scores of the study subjects is increased significantly in follow up assessment times as compared to the pre-program assessment (X2= 186.332, P= 0.001). The post total mean adherence scores of the study subjects is increased significantly in follow up assessment times as compared to the pre-program assessment ( X2= 34.587 , P= 0.001). There is enhancement in some of the laboratory results in follow up assessment times. Effective management of hemodialysis patients is dependent on the recognition that the patient is the main manager. In conclusion patients who were given the educational program represents a higher degree of both knowledge and adherence scores related to their therapeutic regimen as well as enhancement of their laboratory results. Individualization of the common educational approach by incorporating the patient‟s beliefs, behaviors, and emotional and physical feelings as well as culture, economic situation, ability and knowledge of the disease and its treatment supports self- management. So the study recommended, conduction of further studies in order to assess the effectiveness of educational program on patients’ outcome regarding adherence to therapeutic regimen, with replication of this study on a larger probability sample from different geographical locations at the Arab Republic of Egypt.